Fatal Overdoses with EffexorBackWyeth is alerting healthcare professionals about the risk of fatal overdoses occurring in patients taking Effexor and Effexor XR. Effexor (venlafaxine HCl) is an SNRI used to treat major depressive disorder. Wyeth's letter says that patients who overdose on Effexor may have a higher risk of death than patients who overdose on SSRIs, but a lower risk of death than those who overdose with tricyclic antidepressants. It is not clear whether this is due to the toxicity of Effexor in overdose or the characteristics of patients who are treated with this drug. The company points out that the reported overdoses usually occurred in combination with alcohol or other drugs. Several of the most common events associated with overdose include: • Tachycardia • Changes in level of consciousness • Seizures • Mydriasis • Vomiting Other events reported in patients who overdosed included rhabdomyolysis, liver necrosis, serotonin syndrome and death. To reduce the risk of overdose, the company says that healthcare professionals should prescribe Effexor and Effexor XR in the smallest quantity that is consistent with good patient management. Category: News Uploaded: June 6th, 2008 @ 7:25 pm Author: LawsuitGuru Length: 01:24 Rating: Views: Tags: effexor overdose death fda patient safety snri serotonin-norepinephrine reuptake inhibitor depression antidepressant Related Video Links:» View Video Comments For Fatal Overdoses with Effexor » View LawsuitGuru's Other Uploaded Videos Video Thumbnails:Video Embedding Code:* Embed this video on your website, social bookmark, myspace, or blog. |
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